LASER ASSISTED HATCHING FOR HUMAN CRYOPRESERVED CLEAVED EMBRYOS

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Assisted hatching improves implantation rates on cryopreserved-thawed embryos. A randomized prospective study.

BACKGROUND Focus on the hatching process has so far been in the field of fresh embryos. Cryopreserved-thawed embryos have a lower rate of pregnancy than fresh embryos, which might be due to hardening of the zona pellucida. METHODS During a 2 year period, a prospective randomized study enrolling 253 cryopreserved-thawed cycles was performed on day 2 embryos. Pseudorandomization to assisted hat...

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The Use of Laser-assisted Hatching in Bovine in Vitro Produced Embryos to Improve Pregnancy Rate

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Laser-assisted hatching increases pregnancy and implantation rates in cryopreserved embryos that were allowed to cleave in vitro after thawing: a prospective randomized study.

BACKGROUND Cryopreservation of embryos may lead to zona hardening that may compromise in vivo hatching and implantation following thawing and transfer. Assisted hatching (AH) has been advocated as a means of assisting the natural hatching process and enhancing implantation. METHODS The aim of this study was to assess in a prospective randomized manner the effect of laser-assisted hatching (LA...

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Assisted hatching of human embryos: a systematic review and meta-analysis of randomized controlled trials.

BACKGROUND Assisted hatching (AH) is a manipulation of zona pellucida aiming to facilitate embryo implantation. METHODS Systematic review and meta-analysis of medical literature was used to evaluate the effect of AH on assisted reproduction outcomes: clinical pregnancy, live birth, multiple pregnancy and miscarriage. Additional analysis was performed in these subgroups: (i) fresh embryos tran...

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The effects of laser assisted hatching on pregnancy rates

BACKGROUND For infertile women aged over 35 years, failure of the ZP (zona pellucida) to rupture is believed to be associated with a decreased implantation rate in in vitro fertilization (IVF) or intra cytoplasmic sperm injection (ICSI). OBJECTIVE In this research, laser assisted hatching (LAH) was offered to patients with advanced maternal age to evaluate a possible benefit. MATERIALS AND ...

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ژورنال

عنوان ژورنال: LASER THERAPY

سال: 2010

ISSN: 1884-7269,0898-5901

DOI: 10.5978/islsm.19.23